Dr Jasdev Singh
Preimplantation Genetic Testing for Genetic Disorders (PGT-M)
If you or your partner carry a serious inherited condition, embryos can be tested before transfer so that an unaffected embryo can be chosen.
Genetic Testing & Advanced IVF
Lowering the chance of passing on an inherited condition
PGT-M stands for preimplantation genetic testing for monogenic conditions. These are disorders caused by a change in a single gene, such as thalassaemia, cystic fibrosis or spinal muscular atrophy. Embryos created through IVF are tested for the gene change found in your family.
Couples who know they carry a condition often feel a heavy sense of responsibility. Testing embryos offers a way to plan with more information.
Dr Jasdev coordinates with genetic laboratories and counsellors to plan testing around your family’s gene change.
A plan that starts with your results
Your age, history, test results and goals are reviewed before any treatment is suggested.
Clear reasons for each step
You will know why a test or medicine is recommended, what it can do and where its limits are.
Care that stays connected
Reviews are planned around how you respond, your cycle timing and your next decision.
What PGT-M can give you
- Testing designed for the gene change in your family
- Transfer of an embryo found to be unaffected
- Genetic counselling to help you understand your options
How your care is planned
Every stage answers three questions: what is happening, why it matters, and what comes next. The plan is reviewed at each stage and adjusted when needed.
Confirm the gene change and arrange genetic counselling
Prepare a test designed for your family, then start IVF
Test the embryos and transfer an unaffected one
How PGT-M works
First, the laboratory builds a test for your specific gene change, which can take several weeks. You then have IVF or ICSI. Embryos are biopsied at the blastocyst stage and frozen while the cells are tested. An unaffected embryo is then transferred in a later cycle.
Who may benefit
Couples where one or both partners carry a known single gene condition, or who have had a child affected by one. Thalassaemia is relatively common in Malaysia, and carrier couples are among those who may consider this testing.
What to expect
You will start with genetic counselling and a review of the reports confirming the gene change. Preparing the test takes some weeks before IVF begins. Results after the biopsy take around two to three weeks, and you will then plan a frozen transfer together. Genetic counselling continues after treatment, including advice on testing in pregnancy.
How Dr Jasdev works with you
He brings together experience in fertility and gynaecology, and he explains things in plain language. Advice is based on current evidence and on what matters to you. You will always know what the next step is and why it has been suggested. He sees couples from Kuala Lumpur and across Malaysia, as well as some who travel from neighbouring countries.
What to bring to your appointment
Your records help Dr Jasdev understand your history quickly, so more of the visit can go to your questions. If you cannot find everything, bring what you have.
- Genetic test reports for both partners
- Details of affected family members, if known
- Records of any previous IVF or pregnancies
What couples often ask about PGT-M
Most couples arrive with several questions. These common ones can help you plan what to ask.
Can our condition be tested for?
How long does the whole process take?
How accurate is the testing?
Will we need testing in pregnancy as well?
Your questions about PGT-M
What is PGT-M?
It is testing of IVF embryos for a specific inherited gene change, so an unaffected embryo can be chosen for transfer.
Who is it suitable for?
Couples who carry a known single gene condition, such as thalassaemia, or who have a child affected by one. The gene change must be clearly identified first.
What tests are needed first?
Genetic reports confirming the gene change in one or both partners, genetic counselling and the usual IVF tests.
Is it risky?
The embryo biopsy is considered low risk. Testing is designed carefully, but no test is perfect, so a confirmation test in pregnancy may still be advised.
Why see Dr Jasdev for PGT-M?
He coordinates the genetic and fertility steps and explains each stage clearly, so the process feels manageable.
How do I book?
Call or WhatsApp the clinic, and bring any genetic reports you have so planning can start early.
This page is general information and does not replace a consultation. Whether a treatment suits you, and its risks and timing, should be discussed with Dr Jasdev based on your own history.
Plan your family with more information
Book a consultation to discuss genetic testing of embryos.